Our goal is to use cutting-edge optogenetic, imaging, electrophysiological, and molecular biological techniques to gain a better understanding of the brain’s synaptic circuitry as well as the molecular/cellular mechanisms of synaptic function.

Introduction

The Center for Functional Connectomics (CFC) boasts ten research laboratories, all of which use state-of-the-art techniques in molecular biology, imaging, electrophysiology, and neuroinformatics. It tackles brain-related issues at the molecular level, the systemic level, and everything in between. Most of its research focuses on mammalian CNS.

Areas of Interest includes:

  • Developing improved genetically encoded voltage sensors
  • Understanding the cellular/molecular basis of long-term depression
  • Using activity imaging to understand olfactory processing in the olfactory bulb and piriform cortex
  • Measuring brain connectivity at the regional and cellular levels
  • Studying the role of glia in brain function
  • Determining stimulus selectivity of hippocampal “place” cells
  • Imaging the mechanisms of neural circuitry development/remodeling
  • Understanding the functional role of ion channels using protein-protein interaction tools
  • Developing novel, user-friendly software for reconstructing and analyzing brain circuitry
  • Exploring novel roles of intracellular organelles in synaptic function

* The CFC also provides training for postdoctoral researchers and graduate students (PhD or MSc). Please contact the laboratories directly for more information.

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