이이재, Yijae, Lee

Senior Researcher

2023 1st BSI Town hall Meeting (‘23.2.20)

– (일시) 2023년 2월 20일(월) 15:00 – (장소) KIST 커뮤니티라운지 – (내용) 2023년 뇌과학연구소 업무보고, 개인평가, 주요사업 개편 필요성과 방향, FM HI5 등 부서운영 현안과 의견 수렴

2022년 10월 이달의 KIST인상 수상 (뇌질환극복연구단 류훈 박사)

내용: 2022년 10월 이달의 KIST인상 시상식 수상자: 뇌질환극복연구단 류훈 박사 일시: 2022년 12월 13일 (화) 14:10 장소: L7331 류훈 박사님의 이달의KIST인상 수상을 진심으로 축하드립니다 🙂

2022 뇌과학연구소 학술대회(‘22.12.1-2/용평리조트)

ㅇ (일시) 2022년 12월 1일(목) – 2일(금), 2일 간 ㅇ (장소) 용평리조트 그린피아 그랜드볼룸 ㅇ (참석규모) 뇌과학연구소 연구자 약 230명

2022 뇌 연구기관 간 공동연구 성과교류회(‘22.11.29/컨벤션홀)

  ㅇ (일시) 2022년 11월 29일 (화) 10:00 ㅇ (장소) 한국과학기술연구원 국제협력관(L8) 컨벤션홀 ㅇ (공동주최) 한국과학기술연구원 뇌과학연구소(KIST), 기초과학연구원(IBS), 한국뇌연구원(KBRI)

2022 7th BSI FM High Five (‘22.11.7)

  □ (내용) 뇌과학연구소 신규 입원자의 주요 연구성과 발표 – (이주현 박사) Human spinal cord organoids exhibiting neural tube morphogenesis for a quantifiable drug screening system – (임가영 박사) Precise Genome Engineering: from Nucleus to Mitochondria

2022 BSI Special Seminar: Valentin Nägerl (Université de Bordeaux)

[Seminar Detail] – (Title) (Super-resolution) shadow imaging for panoptic visualisation of living brain tissue – (Speaker) Valentin Nägerl (Université de Bordeaux) – (Date&Time) 2022.10.31(Mon) – (Place) L7331

The 2nd KIST BSI & RIKEN-CBS Joint Symposium(‘22.10.11)

2022 BSI Seminar “Neurochemistry & Neuromedicine” Dokyoung Kim(Kyung Hee Univ. of College of Medicine)

[Seminar Detail] – (Title) Creating New Fluorescent Probes for Clinical Applications – (Speaker) Dokyoung Kim(Kyung Hee Univ. of College of Medicine) – (Date&Time) 2022.9.7 (Wed) – (Place) L7331

2022 5th BSI FM High Five (‘22.9.5)

2022 BSI Seminar “Neurobiology” Eun Jeong Lee (Ajou Univ. of School of Medicine)

[Seminar Detail] – (Title) Molecular mapping of stress circuits – (Speaker) Eun Jeong Lee(Ajou Univ. of School of Medicine) – (Date&Time) 2022.8.31(Wed) – (Place) L7331

OFFICE

L7324B, +82-2-958-6743

LAB

L7225

EDUCATION

Ph.D. Electronic Engineering, Kwangwoon University (2013)

M.S. Electronic Engineering, Kwangwoon University (2009)

B.S. Electronic Engineering, Kwangwoon University (2007)

RESEARCH CAREER & ACTIVITIES
  • Senior research scientist, Center for Biomicrosystems, Brain Science Institute, Korea Institute of Science and Technology (KIST) (Aug. 2018-Present)
  • Postdoc Research Associate, Center for Biomicrosystems, Brain Science Institute, Korea Institute of Science and Technology (KIST) (Feb. 2014-Feb. 2018)
  • Postdoc Research Associate, Department of Electronics Engineering, Kwangwoon University (Mar. 2013-Dec. 2013)
RESEARCH INTERESTS
  • BioMEMS, highly catalytic (nanoporous Pt, hybrid coral-like Au with Pt nanoparticles) electrochemical biosensors
  • Dopamine, blood glucose, blood free-cholesterol, hydrogen peroxide, dissolved oxygen
  • Non-invasive, flexible devices for high sensitive low-level analytes determination (Lipoprotein, Neurodegenerative protein)
  • Electrical nerve stimulation/recording for nerve regeneration
  • Minimal-invasive CGMS (Continuous Glucose Monitoring System), Drug delivery micro-pump
  • Micro-TAS (Total Analysis System)
<Impedimetric sensor for low-level cholesterol detection in saliva >
<Multi-channel implantable cuff electrode for PNS application >
< Ink-jet printable and biocompatible sheet-type nerve electrode >
< Foldable sensor (nerve electrode + glucose sensor) for local inflammation monitoring >
<Neural electrode with nanoporous Pt and Micro-needle array with nanoporous Pt >
<Multi-layered nanoporous Pt and hybrid coral-like Au with Pt nanoparticles >
HIGHLIGHT
  • Yi Jae Lee, Changhyuk Lee, Eun Jin Wang, Dmytro Kotov, Hee Youn Kim, Jeong Ho Hwang, Ki Hoon Ahn, and Soo Hyun Lee, “Non-invasive Ring Electrode with a wireless electrical recording and stimulating system for monitoring preterm labor,” IEEE Trans. Neural Systems and Rehabilitation Engineering, 2020 (Equally contributed co-first author)(Accepted)
  • Hyung been Lee, Min Tack Oh, Yi Jae Lee, Kuk Hui Son, Nakwon Choi, Byung Chul Lee, and Soo Hyun Lee, ” Highly-efficient microfluidic ultrasonic transducers assisted gDNA extraction system in whole blood for POCT applications”, Sensors and Actuators B: Chemical, vol. 319(15), 128317, 2020.
  • Kyu Shik Eom, Yi Jae Lee, Hye Won Seo, Ji Yoon Kang, Joon Sub Shim and Soo Hyun Lee, “Sensitive and non-invasive cholesterol determination in saliva via optimization of enzyme loading and platinum nano-cluster composition”, Analyst, 2020, vol. 145, pp. 908-916 (Equally contributed co-first author).
  • Yi Jae Lee, Kyu Shik Eom, Kyeong-Sik Shin, Ji Yoon Kang, and Soo Hyun Lee, “Enzyme-loaded paper combined impedimetric sensor for the determination of the low-level of cholesterol in saliva”, Sensors and Actuators B: Chemical, vol. 271, pp. 73-81, Oct. 2018.
  • Han-Jun Kim, Dong Nyoung Heo, Yi Jae Lee, Sang Jin Lee, Ji Yoon Kang, Soo Hyun Lee, Il Keun Kwon, and Sun Hee Do, “Biological assessments of multifunctional hydrogel-decorated implantable neural cuff electrode for clinical neurology application”, Scientific Reports, vol. 7, 15245, 10 Nov. 2017
  • Dong Nyoung Heo, Han-Jun Kim, Yi Jae Lee, Min Heo, Sang Jin Lee, Donghyun Lee, Sun Hee Do, Soo Hyun Lee, and Il Keun Kwon, “Flexible and highly biocompatible nanofiber-based electrodes for neural surface interfacing”, ACS Nano, vol. 11(3), pp. 2961-2971, Feb. 2017 (DOI: 10.1021/acsnano.6b08390)-Cover paper.
  • Yi Jae Lee, Han-Jun Kim, Ji Yoon Kang, Sun Hee Do, and Soo Hyun Lee, “Biofunctionalization of Nerve Interface via Biocompatible Polymer-Roughened Pt Black on Cuff Electrode for Chronic Recording”, Advanced Healthcare Materials, vol. 6(6), Mar. 2017.
  • Yi Jae Lee, Han Jun Kim, Sun Hee Do, Ji Yoon Kang, and Soo Hyun Lee, “Characterization of Nerve-Cuff Electrode Interface for Biocompatible and Chronic Stimulating Application”, Sensors and Actuators B: Chemical, vol. 237, pp. 924-934, Dec. 2016.
  • Dong Nyoung Heo, Su Jin Song, Han Jun Kim, Yi Jae Lee, Wan Kyu Ko, Sang Jin Lee, Donghyun Lee, Sung Jin Park, Lijie Grace Zhang, Ji Yoon Kang, Sun Hee Do, Soo Hyun Lee, and Il Keun Kwon, “Multifunctional hydrogel coatings on the surface of neural cuff electrode for improving electrode-nerve tissue interfaces”, Acta Biomaterialia, vol. 39, pp. 25-33, Jul. 2016.
  • Yi Jae Lee, Sung Jin Park, Kwang-Seok Yun, Ji Yoon Kang, and Soo Hyun Lee, “Enzymeless glucose sensor integrated with chronically implantable nerve cuff electrode for in-situ inflammation monitoring”, Sensors and Actuators B: Chemical, vol. 222, pp.425-432, Jan. 2016.
  • Sung Jin Park, Yi Jae Lee, Dong Nyoung Heo, Il Keun Kwon, Kwang-Seok Yun, Ji Yoon Kang, and Soo Hyun Lee, “Functional Nerve Cuff Electrode with Controllable Anti-inflammatory Drug Loading and Release by Biodegradable Nanofibers and Hydrogel Deposition”, Sensors and Actuators B: Chemical, vol. 215, pp.133-141, Mar. 2015.
  • Yi Jae Lee and Jae Yeong Park, “Characterization of Electroplated Multilayered Nanoporous Platinum Films for Electrochemical Sensor Applications”, Journal of Nanoscience and Nanotechnology, vol. 13, no. 10, pp. 7067-7069, Oct. 2013.
  • Yi Jae Lee and Jae Yeong Park, “Fabrication and Characterization of Multilayered Nanoporous Platinum Films Deposited by Electroplating and Nonionic Surfactant Molds”, Applied Surface Science, vol. 277, pp. 100-104, Jul. 2013
  • Yi Jae Lee and Jae Yeong Park, “Highly Selective and Sensitive Electrochemical Detection of Dopamine using a Nafion Coated Hybrid Macroporous Gold Modified Electrode with Platinum Nanoparticles”, IEEE Transaction on Nanobioscience, vol. 10, no. 4, pp. 250-258, Dec. 2011.
  • Yi Jae Lee, Cheonseok Oh, Jae Yeong Park, and Younghun Kim, “Fabrication and Characterization of Macroporous Gold Hybrid Sensing Electrodes with Electroplated Platinum Nano-particles”, IEEE Transaction on Nanotechnology, vol. 10, no. 6, pp. 1298-1305, Nov. 2011.
  • Yi Jae Lee and Jae Yeong Park, “A Highly Miniaturized Dissolved Oxygen Sensor Using a Nanoporous Platinum Electrode Electroplated on Silicon”, Journal of Korean Physical Society, vol. 58, no. 5, pp. 1505-1510, May 2011.
  • Yi Jae Lee and Jae Yeong Park, “A Coral-like Macroporous Gold-Platinum Hybrid 3D Electrode for Enzyme-Free Glucose Detection”, Sensors and Actuators B; Chemical, vol. 155, issue 1, pp. 134-139, Jul. 2011.
  • Yi Jae Lee, Jae Yeong Park, Younghun Kim, Jae Wook Ko, “Amperometric Sensing of Hydrogen Peroxide via Highly Roughened Macroporous Gold-/Platinum Nanoparticles Electrode”, Current Applied Physics, vol. 11, pp. 211-216, Mar. 2011.
  • Yi-Jae Lee and Jae-Yeong Park, “Nonenzymatic free-cholesterol detection via a modified highly sensitive macroporous gold electrode with platinum nanoparticles”, Biosensors and Bioelectronics, vol. 26, Issue 4, pp. 1353-1358, Dec. 2010. (Special Issue: Biosensors 2010)
  • Yi-Jae Lee and Jae-Yeong Park, “Fully Embedded Lumped LC-Quadrature Hybrid Coupler into Organic Packaging Substrate for Power Sampling”, Microwave and Optical Technology Letters, vol. 51, no. 3, pp. 845-848, Mar. 2009.
  • Yi Jae Lee, Dae Joon Park, and Jae Yeong Park, “Fully Packaged Non-Enzymatic Glucose Micro-Sensors with Nanoporous Platinum Electrodes for Anti-Fouling”, IEEE SENSORS Journal, vol. 8, no. 11, pp. 1922-1927, Nov. 2008.