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임매순 , Maesoon Im, Ph.D.

Senior Research Scientist

Office

L7325B

Phone

+82 10-2619-0621

+82   2-  958-5749

Homepage

EDUCATION
  • Ph.D. in Electrical Engineering, KAIST (Korea Advanced Institute of Science and Technology), Daejeon, South Korea (Mar 2003 – Aug 2009)
  • B.S. magna cum laude in Electrical Engineering, KAIST, Daejeon, South Korea (Mar 1999 – Feb 2003)
RESEARCH CAREER & ACTIVITIES
  • Senior Research Scientist, Center for BioMicrosystems, Brain Science Institute, KIST (Korea Institute of Science and Technology), Seoul, South Korea (Aug 2018 – Present)
  • Assistant Scientist, Department of Ophthalmology, Henry Ford Health System, Detroit, Michigan, USA  (Nov 2015 – Jul 2018)
    Featured in “Vision & Visionaries” of Henry Ford Health System: https://www.youtube.com/watch?v=ZlRIlMkp1co&feature=youtu.be
  • Adjunct Assistant Professor, Department of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, Michigan, USA (Aug 2016 – Jul 2018)
  • Adjunct Assistant Professor, Department of Electrical and Computer Engineering, Wayne State University College of Engineering, Detroit, Michigan, USA (Nov 2016 – Jul 2018)
  • Research Fellow, Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA (Nov 2011 – Oct 2015)
  • Research Associate, VA Boston Healthcare System, Boston, Massachusetts, USA (Jan 2015 – Sep 2015)
  • Postdoctoral Research Fellow, Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, Michigan, USA (Jun 2010 – Oct 2011)
  • Postdoctoral Researcher, Department of Electrical Engineering, KAIST, Daejeon, South Korea (Sep 2009 – May 2010)
RESEARCH INTERESTS
Postdocs

Young Jun Yoon, Ph.D.

Postdoctoral Researcher (Feb 2019 – present)
EDUCATION

Ph.D., Electrical Engineering, Kyungpook National University, Daegu, South Korea (Feb 2019)

B.S., Electrical Engineering, Kyungpook National University, Daegu, South Korea (Feb 2013)

RESEARCH INTERESTS

3D retinal implant devices, neuromodulation, MEA recording

Graduate Students

Yanjinsuren Otgondemberel

Graduate student of Biomedical Engineering at KIST School, UST (Mar 2019 – present)
EDUCATION

B.S., Bioengineering, National University of Mongolia, Ulaanbaatar, Mongolia (Jun 2018)

RESEARCH INTERESTS

3D retinal implant devices, neuromodulation, MEA recording

We are looking for prospective graduate students who is eager to learn something multidisciplinary and to contribute to the field of neural prosthetics. Please e-mail your CV to Maesoon at maesoon.im@kist.re.kr

We are recruiting passionate graduate students!

대학원생 모집 공고 보기

Research Interns

Sungyoun Hope Kim

Intern (Apr 2019 – Sep 2019)
EDUCATION

B.S., Biology, Yonsei University, Wonju, Gangwon-do, South Korea (Feb 2019)

RESEARCH INTERESTS

3D retinal implant devices, neuromodulation, MEA recording

Ye Ji Jang

Intern (Sep 2019 – Feb 2020)
EDUCATION

Undergraduate Student, Department of Electronic and IT Media Engineering, Seoul National University of Science and Technology, Seoul, South Korea

RESEARCH INTERESTS

Interneuronal correlations of electrically-evoked responses

Alumni

Jae-Ik Lee, Ph.D.

Postdoctoral Researcher (May 2016 – Jul 2018, when the lab was at Henry Ford Health System)
CURRENT POSITION

Postdoctoral Research Fellow, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

EDUCATION

Postdoctoral research fellow, Mechanical Engineering, Yonsei University, Seoul, South Korea (Sep 2015-Apr 2016)

Ph.D., Mechanical Engineering, Yonsei University, Seoul, South Korea (Aug 2015)

B.S., Mechanical Engineering, Yonsei University, Seoul, South Korea (Feb 2008)

RESEARCH INTERESTS

Retinal prosthesis, neuromodulation

Sooyoung Lee

Intern (Jan – Feb 2019)
EDUCATION

Undergraduate Student, Department of Animal Biotechnology, Chung Ang University, Ansung, South Korea

RESEARCH INTERESTS

Optimization of MATLAB code for artifact removal and spike detection

Ryan Leman

Intern (Jun – Jul 2019)
EDUCATION

Undergraduate Student, Department of Psychology, University of Colorado, Denver, CO, USA

RESEARCH INTERESTS

Creation and modification of human perceptual, sensational and cognitive capabilities

Seungki An

Intern (Jun 2019 – Aug 2019)
EDUCATION

Undergraduate Student, School of Computer and Information Engineering, Kwangwoon University, Seoul, South Korea

RESEARCH INTERESTS

Correlation level of visually-evoked and electrically-evoked spiking patterns

Kwangjun Kim

Intern (Jul 2019 – Aug 2019)
EDUCATION

Undergraduate Student, Department of Mechanical and Automotive Engineering, Seoul National University of Science and Technology, Seoul, South Korea

RESEARCH INTERESTS

3D retinal implant devices using carbon nanotube bundles

Neural Engineering
Retinal Prosthesis (Bionic Eye)

Our main research topic is retinal prosthetics, which is a specific research area of neural engineering. The field of retinal prosthetics is at the intersection of electrical engineering and neuroscience, particularly microfabrication/BioMEMS and retinal neurophysiology. As one of neural prosthetics, microelectronic retinal prosthetic systems (a.k.a bionic eye) have restored some level of useful vision to individuals blinded by retinitis pigmentosa (RP) or age-related macular degeneration (AMD). At this moment, there are three bionic eye systems (Argus II of Second Sight, Alpha-AMS of Retina Implant, IRIS of Pixium Vision) are commercially available around the world. But, the best performance is still sub-optimal and far away from normal vision. For significantly enhanced artificial vision (e.g. improved spatial resolution), a technical breakthrough should take place in implantable microelectrode arrays using microfabrication technologies. However, the limited performance of existing state-of-the-art devices suggests a game-changing innovation requires much deeper understanding of the retina. Our previous works (Im and Fried, J. Physiol., 2015; Im and Fried, J. Neural Eng., 2016; Im et al., J. Neural Eng., 2018; Lee and Im, J. Neural Eng., 2018) have substantially increased our understanding of properties of retinal neurons in response to electric stimulation. We are eager to develop advanced next-generation retinal implants using new insights obtained from those studies as well as our expertise in micro-/nano-fabrication.

probes
Other Neural Prostheses

The eventual objective of our long-term research is to promote the quality of health care by integration of electrical engineering and neuroscience. For example, the insights from our research in the retina are likely to be applicable to other parts of the central nervous system (CNS). Therefore, our future research will be expanded to more diverse applications such as visual cortex stimulation for other types of vision loss, deep brain stimulation (DBS; What is DBS? – youtube; Before & After DBS – youtube) for neurological disorders, and spinal cord stimulation (a.k.a bionic spine; Paralysed Rats Made to Walk Again – youtube) for movement disorders. Research methods similar to those we have performed in the retina can be carried out to reveal mechanisms underlying electrically-evoked responses arising in the aforementioned parts of CNS. Also, novel implantable electrode arrays can be developed for those applications.

Visual Neuroscience
Retinal Neurophysiology

To make electrically-elicited artificial vision more ‘natural’, it is essential to understand response patterns arising from complex ‘natural’ stimulus in each type of retinal ganglion cells (RGCs). Typically, however, high contrast spot flashes and moving bars have been used for analysis of RGC responses. In contrast to these laboratory stimuli, our visual world is remarkably complex. During the study of their responses to natural movies, we found an interesting feature of directionally selective (DS) ganglion cells; The DS ganglion cells of the retina respond preferentially to movement in a preferred direction, but under laboratory conditions, they are also sensitive to changes in the luminance. This raises the classic problem of how the cells can reliably signal the direction of motion if the responses are confounded by both direction and luminance. Thus, during situations in which both stimuli are found, e.g. natural viewing, the brain must determine if a given burst of spikes carries information about motion or about luminance. We developed a method to separate motion and luminance responses and found that in striking contrast to much previous work, luminance responses in DS cells are strongly suppressed during natural viewing (Im and Fried, Sci. Rep., 2016). As a result, spiking from the DS cell conveys a relatively pure signal of direction to be transmitted to the brain and downstream processing is greatly simplified. This study assured that RGC responses to natural stimuli are markedly different from those to laboratory stimuli. We are going to explore the retinal neural circuitry to better understand how this complex computation is possible.

DSresponses
Micro-/Nano-Devices
Electrical/Mechanical Devices for Biological Applications

My research spectrum covers from transistors to retinal neurons, which are basic building blocks of modern electronics and nervous systems, respectively. My Ph.D. thesis work includes the development of a nanowire channel thin-film transistor (TFT), which was the world’s smallest TFT at the time of publication (Im et al., IEEE Elect. Dev. Lett., 2008). In my dissertation, I further explored the use of a similar type of nanowire channel transistors for detection of avian influenza virus (Im et al., IEEE Sensors J., 2011). Another research area in my graduate studies was Micro-Electro Mechanical Systems (MEMS): I developed MEMS devices for diverse applications such as biological assay patterning (Im et al., Appl. Phys. Lett., 2007), super-hydrophobicity (Im et al., Soft Matter, 2010; Im et al., Langmuir, 2010a), and electrowetting (Im et al., Langmuir, 2010b). From these studies, I acquired various hands-on skills for cutting-edge micro-/nano-fabrication research.

During my postdoctoral training at the University of Michigan, I had worked on a more advanced MEMS device with a neural engineering application. For selective excitation of genetically modified neurons using accurately transmitted light (i.e. optogenetics), I had fabricated neural probes with monolithically integrated optical waveguides (Im et al., IEEE MEMS, 2011; Im et al., IEEE EMBC, 2011; Fan et al., J. Neural Eng., 2013). Those neural probes also have integrated microelectrodes for recording neural activities as a precise tool for neuroscience studies. Prior to this type of research, neuroscientists used to manually attach a chemically-thinned optical fiber onto neural probes. It was a good example showing that MEMS devices can provide an enabling technology to neuroscientists for more accurately controlled experiments. During that time, I realized that micro-/nano-fabrication expertise could contribute even further to neuroscience if micro-/nano-fabrication engineers gain fundamental understandings and direct research experience with a specific topic.

Google Scholar Page
Peer-Reviewed Journal Papers
  1. Jae-Ik Lee and Maesoon Im, “Optimal electric stimulus amplitude improves the selectivity between responses of ON versus OFF types of retinal ganglion cells,” IEEE Transactions on Neural Systems and Rehabilitation Engineering, In press, DOI: 10.1109/TNSRE.2019.2939012.
    – This work shows intermediate amplitudes of current stimuli may result in more natural artificial vision arising from retinal implant.
  2. Jae-Ik Lee and Maesoon Im, “Non-rectangular waveforms are more charge-efficient than rectangular one in eliciting network-mediated responses of ON type retinal ganglion cells,” Journal of Neural Engineering, Vol.15, No.5, 055004 (17pp), Aug. 2018.
    – This work shows non-standard (i.e. non-rectangular) pulse waveforms can maximize the efficacy of neuronal responses to electric stimulation.
  3. Maesoon Im, Paul Werginz and Shelley I. Fried, “Electric stimulus duration alters network-mediated responses depending on retinal ganglion cell type,” Journal of Neural Engineering, Vol.15, No.3, 036010 (15pp), Mar. 2018.
    – This work demonstrates a specific range of stimulus duration can maximize the signal-to-noise ratio of neuronal responses of the retina to electric stimulation.
  4. Jae-Hyuk Ahn, Sung-Jin Choi, Maesoon Im, Sungho Kim, Jin-Woo Han, Chang-Hoon Kim, Jee-Yeon Kim, Tae Jung Park, Sang Yup Lee, and Yang-Kyu Choi, “Charge and dielectric effects of biomolecules on electrical characteristics of nanowire FET biosensors,” Applied Physics Letters, Vol.111, No.11, 113701 (5pp), Sep. 2017.
  5. Maesoon Im and Shelley I. Fried, “Directionally selective retinal ganglion cells suppress luminance responses during natural viewing,” Scientific Reports, Vol. 6, 35708 (9pp), DOI: 10.1038/srep35708, Oct. 2016.
    – This work resolves a long-standing paradox related to the neural computation performed by directionally selective ganglion cells of the retina as to how downstream neurons distinguish information about motion from information about luminance.
  6. Maesoon Im and Shelley I. Fried, “Temporal properties of network-mediated responses to repetitive stimuli are dependent upon retinal ganglion cell type,” Journal of Neural Engineering, Vol.13, No.2, 025002 (13pp), Feb. 2016.
    – This work offers insight to retinal prosthetics community regarding preferred stimulation rates of 5-7 Hz observed in previous clinical trials.
  7. Maesoon Im and Shelley I. Fried, “Indirect activation elicits strong correlations between light and electrical responses in ON but not OFF retinal ganglion cells,” The Journal of Physiology, Vol.593, No.16, pp.3577-3596, Aug. 2015.
    – This work is the first report providing physiological background how retinal prosthetics users perceive bright phosphenes (ON responses) even with non-selective activation of various cell types.
  8. Jae-Hyuk Ahn, Maesoon Im, Tae Jung Park, Sang Yup Lee, and Yang-Kyu Choi, “Label-free and real-time detection of avian influenza using nanowire field effect transistors,” Journal of Biomedical Nanotechnology, Vol.11, No.9, pp.1640-1643, Sep. 2015.
  9. Fan Wu, Eran Stark, Maesoon Im, Il-Joo Cho, György Buzsáki, Kensall D. Wise, and Euisik Yoon, “An implantable neural probe with monolithically integrated optical waveguide and recording electrodes for optogenetics applications,” Journal of Neural Engineering, Vol.10, No.5, 056012 (9pp), Aug. 2013.
    Primary microfabrication engineer of the device presented in this work.
    – Selected as the Journal of Neural Engineering Highlights of 2013.
  10. Maesoon Im, Kyungyong Choi, Dong-Haan Kim, Joo-Hyung Lee, Jun-Bo Yoon, and Yang-Kyu Choi, “Adhesion force change by electrowetting on a polymer microlens array,” Journal of Adhesion Science and Technology, Vol.26, No.12-17, pp.2079-2086, May, 2012. (Invited Paper)
  11. Kyungyong Choi, Jee-Yeon Kim, Jae-Hyuk Ahn, Ji-Min Choi, Maesoon Im, and Yang-Kyu Choi, “Integration of field effect transistor-based biosensors with a digital microfluidic device for a lab-on-a-chip application,” Lab on a Chip, Vol.12, No.8, pp.1533-1539, Mar. 2012.
  12. Jee-Yeon Kim, Jae-Hyuk Ahn, Sung-Jin Choi, Maesoon Im, Sungho Kim, Chang-Hoon Kim, Tae Jung Park, Sang Yup Lee, and Yang-Kyu Choi, “An underlap channel-embedded field-effect transistor for biosensor application in watery and dry environment,” IEEE Transactions on Nanotechnology, Vol.11, No.2, pp.390-394, Mar. 2012.
  13. Kyungyong Choi, Maesoon Im, Ji-Min Choi, and Yang-Kyu Choi, “Droplet transportation using a pre-charging method for digital microfluidics,” Microfluidics and Nanofluidics, Vol.12, No.5, pp.821-827, Mar. 2012.
  14. Oktay Yarimaga, Sumi Lee, Daeyoung Ham, Ji-Min Choi, Soon Gyu Kwon, Maesoon Im, Sungho Kim, Jong-Man Kim, and Yang-Kyu Choi, “Thermofluorescent conjugated polymer sensors for nano/microscale temperature monitoring,” Macromolecular Chemistry and Physics, Vol.212, No.12, pp.1211-1220, Jun. 2011. (Highlighted as a Front Cover)
  15. Maesoon Im, Jae-Hyuk Ahn, Jin-Woo Han, Tae Jung Park, Sang Yup Lee, and Yang-Kyu Choi, “Development of a point-of-care testing platform with a nanogap-embedded separated-double gate field effect transistor array and its readout system for detection of avian influenza,” IEEE Sensors Journal, Vol.11, No.2, pp.351-360, Feb. 2011.
  16. Yong-Bum Park, Hwon Im, Maesoon Im, and Yang-Kyu Choi, “Self-cleaning effect of highly water-repellent microshell structures for solar cell applications,” Journal of Materials Chemistry, Vol.21, No.3, pp.633-636, Jan. 2011.
  17. Maesoon Im, Hwon Im, Joo-Hyung Lee, Jun-Bo Yoon, and Yang-Kyu Choi, “Analytical modeling and thermodynamic analysis of robust superhydrophobic surfaces with inverse-trapezoidal microstructures,” Langmuir, Vol.26, No.22, pp.17389-17397, Sep. 2010.
  18. Maesoon Im, Dong-Haan Kim, Joo-Hyung Lee, Jun-Bo Yoon, and Yang-Kyu Choi, “Electrowetting on a polymer microlens array,” Langmuir, Vol.26, No.14, pp.12443-12447, Jul. 2010.
  19. Yong-Bum Park, Maesoon Im, Hwon Im, and Yang-Kyu Choi, “Superhydrophobic cylindrical nanoshell array,” Langmuir, Vol.26, No.11, pp.7661-7664, Jun. 2010.
  20. Oktay Yarimaga, Maesoon Im, Yang-Kyu Choi, Tae Won Kim, Yun Kyung Jung, Hyun Gyu Park, Sumi Lee, and Jong-Man Kim, “A color display system based on thermochromic conjugated polydiacetylene supramolecules,” Macromolecular Research, Vol.14, No.4, pp.404-407, Apr. 2010.
  21. Maesoon Im, Hwon Im, Joo-Hyung Lee, Jun-Bo Yoon, and Yang-Kyu Choi, “A robust superhydrophobic and superoleophobic surface with inverse-trapezoidal microstructures on a large transparent flexible substrate,” Soft Matter, Vol.6, No.7, pp.1401-1404, Apr. 2010.
  22. Hong-Xuan Ren, Xing Chen, Xing-Jiu Huang, Maesoon Im, Dong-Haan Kim, Joo-Hyung Lee, Jun-Bo Yoon, Ning Gu, Jin-Huai Liu, and Yang-Kyu Choi, “A conventional route to scalable morphology-controlled regular structures and their superhydrophobic/hydrophilic properties for biochips application,” Lab on a Chip, Vol.9, No.15, pp.2140–2144, Jul. 2009.
  23. Xing-Jiu Huang, Dong-Haan Kim, Maesoon Im, Joo-Hyung Lee, Jun-Bo Yoon, and Yang-Kyu Choi, “‘Lock-and-Key’ geometry effect of patterned surfaces: the wettability and the switching of adhesive force,” small, Vol.5, No.1, pp.90–94, Jan. 2009.
  24. Jin-Woo Han, Seong-Wan Ryu, Chung-Jin Kim, Sungho Kim, Maesoon Im, Sung Jin Choi, Jin Soo Kim, Kwang Hee Kim, Gi Sung Lee, Jae Sub Oh, Myeong Ho Song, Yun Chang Park, Jeoung Woo Kim, and Yang-Kyu Choi, “Partially-depleted SONOS FinFET for unified RAM (URAM) – unified function for high speed 1T DRAM and nonvolatile memory,” IEEE Electron Device Letters, Vol.29, No.7, pp.781–783, Jul. 2008.
  25. Maesoon Im, Jin-Woo Han, Hyunjin Lee, Lee-Eun Yu, Sungho Kim, Chang-Hoon Kim, Sang Cheol Jeon, Kwang Hee Kim, Gi Sung Lee, Jae Sub Oh, Yun Chang Park, Hee Mok Lee, and Yang-Kyu Choi, “Multiple-gate CMOS thin-film transistor with polysilicon nanowire,” IEEE Electron Device Letters, Vol.29, No.1, pp.102–105, Jan. 2008.
    – This work reported the World’s smallest thin-film transistor (TFT) at the time of publication.
  26. Seong-Jin Kim, Kyutae Yoo, Jeoyoung Shim, Wonseok Chung, Christopher Ko, Maesoon Im, Lee-Sup Kim, and Euisik Yoon, “Real-time label-free quantitative monitoring of biomolecules without surface binding by floating-gate complementary metal-oxide semiconductor sensor array integrated with readout circuitry,” Applied Physics Letters, Vol.91, No.20, 203903 (3pp), Nov. 2007.
  27. Maesoon Im, Il-Joo Cho, Kwang-Seok Yun, and Euisik Yoon, “Electromagnetic actuation and microchannel engineering of a polymer micropen array integrated with microchannels and sample reservoirs for biological assay patterning,” Applied Physics Letters, Vol.91, No.12, 124101 (3pp), Sep. 2007.
    – Selected by Virtual Journal of Biological Physics Research (Vol.14, No.7, Oct. 2007), which is an edited compilation of links to articles from participating publishers, converting a focused area of frontier research.
International Conference
  1. Jae-Ik Lee and Maesoon Im, “OFF types of mouse retinal ganglion cells are less sensitive to a change in electric stimulus charge than ON type,” The 9th International IEEE EMBS Conference on Neural Engineering (NER), pp.227-230, San Francisco, CA, USA, Mar. 20-23, 2019.
  2. Paul Werginz, Maesoon Im, Alex E. Hadjinicolaou, and Shelley I. Fried, “Visual and electrical spiking signatures of seven types of rabbit retinal ganglion cells,” The 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’18), pp.2434-2437, Honolulu, HI, USA, Jul. 17-21, 2018.
  3. Jae-Ik Lee and Maesoon Im, “Non-rectangular waveforms are more charge-efficient for network-mediated responses of ON type retinal ganglion cells,” The 2018 Association for Vision Research and Ophthalmology (ARVO) Annual Meeting, Honolulu, HI, USA, Apr. 29-May 3, 2018.
  4. Maesoon Im, Jae-Ik Lee, and Shelley I. Fried, “Network-mediated responses of ON ganglion cells to electric stimulation alter over the course of retinal degeneration,” The Eye and The Chip (The 10th World Research Congress on the Relationship between Neurobiology and Nano-Electronics Focusing on Artificial Vision), Detroit, MI, USA, Sep. 24-26, 2017.
  5. Jae-Ik Lee, Shelley I. Fried, and Maesoon Im, “Network-mediated responses of ON ganglion cells to electric stimulation become less consistent across trials during retinal degeneration,” The Eye and The Chip (The 10th World Research Congress on the Relationship between Neurobiology and Nano-Electronics Focusing on Artificial Vision), Detroit, MI, USA, Sep. 24-26, 2017.
  6. Jae-Ik Lee, Shelley I. Fried, and Maesoon Im, “Network-mediated responses of ON ganglion cells to electric stimulation become less consistent across trials during retinal degeneration,” The 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’17), pp.2114-2117, Jeju, South Korea, Jul. 11–15, 2017.
  7. Jae-Ik Lee, Shelley I. Fried, and Maesoon Im, “Network-mediated responses of ON ganglion cells to electric stimulation change over the course of retinal degeneration,” The 2017 Association for Vision Research and Ophthalmology (ARVO) Annual Meeting, Baltimore, MD, USA, May 7-11, 2017.
  8. Maesoon Im and Shelley I. Fried, “Electric stimulus duration modulates network-mediated responses depending on ganglion cell type,” The Eye and The Chip (The 9th Biennial World Research Congress on the Relationship between Neurobiology and Nano-Electronics Focusing on Artificial Vision), Dearborn, MI, USA, Sep. 18-20, 2016.
  9. Maesoon Im and Shelley I. Fried, “Electric stimulus duration alters network-mediated responses depending on retinal ganglion cell type,” The 2016 Association for Vision Research and Ophthalmology (ARVO) Annual Meeting, Seattle, WA, USA, May 1-5, 2016.
  10. Maesoon Im and Shelley I. Fried, “Temporal properties of network-mediated responses to repetitive stimuli are different in ON vs. OFF retinal ganglion cells,” The 2015 Association for Vision Research and Ophthalmology (ARVO) Annual Meeting, Denver, CO, USA, May 3-7, 2015.
  11. Maesoon Im and Shelley I. Fried, “Spatial properties of network-mediated response of retinal ganglion cells to electric stimulation,” The 7th International IEEE EMBS Conference on Neural Engineering (NER), pp.256-259, Montpellier, France, Apr. 22-24, 2015.
  12. Maesoon Im and Shelley I. Fried, “Network-mediated activation elicits strong correlations between light and electrical responses in ON but no OFF ganglion cells,” The Eye and The Chip (The 8th Biennial World Research Congress on the Relationship between Neurobiology and Nano-Electronics Focusing on Artificial Vision), Dearborn, MI, USA, Sep. 28-30, 2014.
  13. Maesoon Im and Shelley I. Fried, “Indirect activation elicits strong correlations between light and electrical responses in ON but not OFF ganglion cells,” The 2014 Association for Vision Research and Ophthalmology (ARVO) Annual Meeting, Orlando, FL, USA, May 4-8, 2014.
  14. Fan Wu, Eran Stark, Maesoon Im, Il-Joo Cho, Lee Tien, Fujun Chen, Eui-Sung Yoon, Gyorgi Buzsaki, David Kaplan, Josh Berke, Kensall D. Wise, and Euisik Yoon, “Implantable neural probes for chronic electrical recording and optical stimulation,” IEEE International Electron Devices Meeting (IEDM), pp.216-219, Washington, D.C., USA, Dec. 9–11, 2013. (Invited talk)
  15. Maesoon Im and Shelley I. Fried, “ON-OFF DS ganglion cells detect motion and suppress luminance responses during natural viewing,” The 2013 Association for Vision Research and Ophthalmology (ARVO) Annual Meeting, Seattle, WA, USA, May 5-9, 2013.
  16. Patrick Ingram, Maesoon Im, Sean McDermott, Max Wicha, and Euisik Yoon, “Spheroid cell culture on PDMS hydrophobic surfaces and integration into microfluidic devices,” The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS), pp.1539-1541, Seattle, WA, USA, Oct. 2-6, 2011.
  17. Maesoon Im, Il-Joo Cho, Fan Wu, Kensall D. Wise, and Euisik Yoon, “A dual-shank neural probe integrated with double waveguides on each shank for optogenetic applications,” The 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’11), pp.5480-5483, Boston, MA, USA, Aug. 30- 3, 2011.
  18. HyungDal Park, Hyun-Joon Shin, Il-Joo Cho, Eui-Sung Yoon, Jun-Kyo Francis Suh, Maesoon Im, Euisik Yoon, Yong-Jun Kim, and Jinseok Kim, “The first neural probe integrated with light source (blue laser diode) for optical stimulation and electrical recording,” The 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC’11), pp.2961-2964, Boston, MA, USA, Aug. 30- 3, 2011.
  19. Fan Wu, Maesoon Im, and Euisik Yoon, “A flexible fish-bone-shaped neural probe strengthened by biodegradable silk coating for enhanced biocompatibility,” The 16th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers), pp.966-969, Beijing, China, Jun. 5-9, 2011.
  1. Maesoon Im, Il-Joo Cho, Fan Wu, Kensall D. Wise, and Euisik Yoon, “Neural probes integrated with optical mixer/splitter waveguides and multiple stimulation sites,” The 24th IEEE International Conference on Micro Electro Mechanical Systems (MEMS),1051-1054, Cancun, Mexico, Jan. 23-27, 2011.
  1. Hwon Im, Yong-Bum Park, Jinkyu Suk, Maesoon Im, Cheol O Joe, and Yang-Kyu Choi, “A hemocompatible array of cylindrical nanoshells with a reduced effective blood contact area,” The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS), pp.1940-1942, Groningen, The Netherlands, Oct. 3–7, 2010.
  2. Jae-Hyuk Ahn, Jee-Yeon Kim, Maesoon Im, Jin-Woo Han, and Yang-Kyu Choi, “A nanogap-embedded nanowire field effect transistor for sensor applications: immunosensor and humidity sensor,” The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS), pp.1301-1303, Groningen, The Netherlands, Oct. 3–7, 2010.
  3. Maesoon Im, Dong-Haan Kim, Joo-Hyung Lee, Jun-Bo Yoon, and Yang-Kyu Choi, “Densely-packed microbowl array with balanced dielectrophoretic forces for single-cell microarray,” 2009 Materials Research Society (MRS) Fall Meeting, Boston, MA, USA, Nov. 30–Dec. 3, 2009.
  4. Maesoon Im, Hwon Im, Dong-Haan Kim, Joo-Hyung Lee, Jun-Bo Yoon, and Yang-Kyu Choi, “Analysis of a superhydrophobic microlens array surface: as a microchannel wall for pressure drop reduction,” The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS),162–164, Jeju, South Korea, Nov. 1–5, 2009.
  5. Maesoon Im, Dong-Haan Kim, Xing-Jiu Huang, Joo-Hyung Lee, Jun-Bo Yoon, and Yang-Kyu Choi, “A highly flexible superhydrophobic microlens array with small contact angle hysteresis for droplet-based microfluidics,” The 22nd IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp.475–478, Sorrento, Italy, Jan. 25–29, 2009.
  6. Maesoon Im, Jae-Hyuk Ahn, and Yang-Kyu Choi, “Integrated current readout circuit and DMFET array for label-free detection of cancer marker,” International SoC Design Conference (ISOCC) 2008, Vol.3, pp.66–67, Busan, South Korea, Nov. 24–25, 2008.
  7. Jae-Hyuk Ahn, Maesoon Im, and Yang-Kyu Choi, “Label-free electrical detection of PSA by a nanogap field effect transistor,” The 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS), pp.979–981, San Diego, CA, USA, Oct. 12–16, 2008.
  8. Maesoon Im, Jae-Hyuk Ahn, and Yang-Kyu Choi, “Label-free cancer marker detection platform with cartridge-like DMFET array and current readout circuitry,” International Conference on Biosensors, Biochips, and Bioelectronic Devices (BIOTRONICS 2008), p.73, Jeju, South Korea, Oct. 8, 2008.
  9. Oktay Yarimaga, Maesoon Im, Bonsang Gu, Tae Won Kim, Yun Kyung Jung, Hyun Gyu Park, and Yang-Kyu Choi, “Thermally actuated organic display device using thermo-chromatic polymer composite film with self-aligned patterns,” The 21st IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp.750–753, Tucson, AZ, USA, Jan. 13–17, 2008.
  10. Jin-Woo Han, Seong-Wan Ryu, Chungjin Kim, Sungho Kim, Maesoon Im, Sung Jin Choi, Jin Soo Kim, Kwang Hee Kim, Gi Sung Lee, Jae Sub Oh, Myeong Ho Song, Yun Chang Park, Jeoung Woo Kim, and Yang-Kyu Choi, “A unified-RAM (URAM) cell for multi-functioning capacitorless DRAM and NVM,” IEEE International Electron Devices Meeting (IEDM), pp.929–932, Washington, D.C., USA, Dec. 10–12, 2007.
  11. Maesoon Im, Jin-Woo Han, Hyunjin Lee, Lee-Eun Yu, Sungho Kim, Chang-Hoon Kim, Sang Cheol Jeon, Kwang Hee Kim, Gi Sung Lee, Jae Sub Oh, Yun Chang Park, Hee Mok Lee, and Yang-Kyu Choi, “Novel polysilicon thin-film transistors with nanowire channel,” Semiconductor Technology for Ultra Large Scale Integrated Circuits and Thin Film Transistors, Barga, Italy, Jul. 29–Aug. 3, 2007.
  12. Oktay Yarimaga, Tae Won Kim, Yun Kyung Jung, Maesoon Im, Bonsang Gu, Hyun Gyu Park, and Yang-Kyu Choi, “A new patterning technique on UV sensitive transparent film with chip embedded photomask,” The 15th Asia-Pacific Workshop on Fundamental and Application of Advanced Semiconductor Devices (AWAD), pp.320–323, Gyeongju, South Korea, Jun. 25–27, 2007.
  13. Hyunjin Lee, Seong-Wan Ryu, Jin-Woo Han, Lee-Eun Yu, Maesoon Im, Chungjin Kim, Sungho Kim, Eujune Lee, Kuk-Hwan Kim, Ju-Hyun Kim, Dong-il Bae, Sang Cheol Jeon, Kwang Hee Kim, Gi Sung Lee, Jae Sub Oh, Yun Chang Park, Woo Ho Bae, Jung Jae Yoo, Jun Mo Yang, Hee Mok Lee, and Yang-Kyu Choi, “A nanowire transistor for high performance logic and terabit non-volatile memory devices,” Symposium on VLSI Technology, pp.144–145, Kyoto, Japan, Jun. 12–14, 2007.
  14. Maesoon Im, Seong-Jin Kim, Kyutae Yoo, Jeoyoung Shim, Kyusang Lee, Younja Cho, Wonseok Chung, Christopher Ko, and Euisik Yoon, “Non-surface-binding label-free quantification of PCR product with fast and sequential detection capability,” The 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS), pp.762–764, Tokyo, Japan, Nov. 5–9, 2006.
  15. Youn-Suk Choi, Young-Ji Kim, Maesoon Im, Byoung-Gyun Kim, Kwang-Seok Yun, and Euisik Yoon, “Three dimensional electrode structure controlled by dielectrophoresis for flow-through micro electroporation system,” The 19th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 466–469, Istanbul, Turkey, Jan. 22–26, 2006.
  16. Maesoon Im, Il-Joo Cho, Kwang-Seok Yun, and Euisik Yoon, “An electromagnetically-actuated polymer micro-pen for picoliter biological assay patterning,” The 13th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers), pp.1588–1591, Seoul, South Korea, Jun. 5–9, 2005.
Book Chapters
  1. Maesoon Im and Yang-Kyu Choi, “Point-of-care testing platform with nanogap-embedded field effect transistor,” Chapter 18 in Novel Advances in Microsystems Technologies and Their Applications (ISBN 978-1-4665-6066-6), pp. 413-436, Laurent A. Francis, Krzysztof Iniewski, Ed. CRC Press, Jul. 26, 2013.
  2. Maesoon Im and Yang-Kyu Choi, “Numerical analysis and simulation of fluidics in nanogap-embedded separated double-gate field effect transistor for biosensor,” Chapter 11 in New Perspectives in Biosensors Technology and Applications (ISBN 978-953-307-448-1), pp.229-244, Pier Andrea Serra, Ed. InTech, Jul. 27, 2011. DOI: 10.5772/16972.
Playing & Watching Basketball
Fun_page
Ye Ji has joined the lab as a research intern in Sep 2019.
Kwangjun has joined the lab as a research intern in Jul 2019.
Seungki has joined the lab as a research intern in Jun 2019.
Ryan has joined the lab as a research intern in Jun 2019.
Sungyoun has joined the lab as a research intern in Apr 2019.
Yanjinsuren has joined the lab as a graduate student in Mar 2019.
Young Jun has joined the lab as a postdoc in Feb 2019.
Sooyoung has joined the lab as a winter intern in Jan 2019.
The Im Lab at KIST has opened in Aug 2018.
Information

We are currently seeking exceptional candidates who would share our passion for impactful research. Our lab is studying Neural Engineering for various neural prosthetic applications such as retinal implant which aims to restore sight to blind individuals. The field of Neural Prosthetics is at the intersection of Electrical Engineering and Neuroscience. Given the multidisciplinary nature of our research, the lab is open to passionate candidates from diverse disciplines. If you are interested in joining our lab, please email Maesoon at maesoon.im@kist.re.kr

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