이상희, Lee, Sanghee
Senior Researcher
EDUCATION
Ph.D. Chemical Biology, Department of Chemistry, Seoul National University (2014)
B.S. Chemical education, Seoul National University (2008)
RESEARCH CAREER & ACTIVITIES
- Adjunct professor, Department of HY-KIST Bio-convergence, Hanyang University (2020-current)
- Senior Researcher, Brain Science Institute, Korea Institute of Science and Technology (KIST) (2017-Present)
- Postdoctoral Research Fellow, Fundamental Signaling Research Hub, Department of Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research (NIBR) (2015-2017)
- Postdoctoral Research Fellow, Department of Chemistry, Seoul National University (2014)
RESEARCH INTERESTS
- Discovery of new signaling pathway
- Identification of bioactive small-molecule modulators and mode-of-action study
- Development of sensors and chemical probes
HIGHLIGHT
- Development of Potent Immune-modulators Targeting Stimulator of Interferon Genes Receptor. Jeon.M.J.‡; Lee.H.‡; Lee. J.; Baek,S.Y.; Lee. D.; Jo.S.; Lee. J-Y.; Kang.M.; Jung. H. R.; Han. S. B.; Kim.N-J.; Lee.S.*; Kim.H.* J. Med. Chem. 2022, 65, 5407. (selected as a supplemental cover)
- A Tetrazine fused aggregation induced emission luminogen for bioorthogonal fluorogenic molecular bioimaging with spatiotemporal control. Choi,S-K.; Lee, Y.; Yoon, S.E.; Choi.S.; Kim. J.; Kim. J.H.; Lee, S.*; Kim, W.*; Kim, E.* Sensors & Actuators, B: Chemical. 2021, 340, 129966.
- A small molecule binding HMGB1 and HMGB2 inhibits microglia-mediated neuroinflammation. Lee, S.; Nam, Y.; Koo, J.Y.; Lim, D.; Park, J.; Ock, J.; Kim, J.; Suk, K.*; Park, S.B.* Nat. Chem. Biol. 2014, 10, 1055–1060.