추현아, Choo, Hyunah

Principal Researcher

OFFICE

L2215, +82-958-5157

LAB

L2226-7, L2147, +82-958-5167/5120

HOMEPAGE

EDUCATION

Ph.D. Medicinal Chemistry, College of Pharmacy, The University of Georgia at Athens (2003)
M.S. Organic Chemistry, Seoul National University (1996)
B.S. Chemistry, Seoul National University (1993)

RESEARCH CAREER & ACTIVITIES
  • Principal Researcher, Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology (KIST) (2005-Present)
  • Postdoctoral Research Fellow, Department of Medicine, University of California at San Diego (2003-2004)
RESEARCH INTERESTS
  • Discovery of GPCR Modulators (G protein/b-arrestin biased ligands)
  • Discovery of NIR and PET Probes for Diagnosis of Neurodegenerative Diseases
  • Development of Drug Candidates for Depression, Sleep Disorders and AD/PD
HIGHLIGHT
  • A Difluoroboron b-Diketonate Probe Shows “Turn-on” Near-Infrared Fluorescence Specific for Tau Fibrils. Park, K.-s.; Kim, M.K.; Seo, Y.; Ha, T.; Yoo, K.; Hyeon, S.J.; Hwang, Y.J.; Lee, J.; Ryu, H.; Choo, H.*; Chong, Y.* ACS Chem. Neurosci. 2017, 8, 2124–2131.
  • Indole-Substituted Benzothiazoles and Benzoxazoles as Selective and Reversible MAO-B Inhibitors for Treatment of Parkinson’s Disease. Nam, M.-H.; Park, M.; Park, H.; Kim, Y.; Yoon, S.; Sawant, V.S.; Choi, J.W.; Park, J.H.; Park, K.D.; Min, S.-J.; Lee, C.J.; Choo, H.* ACS Chem. Neurosci. 2017, 8, 1519–1529.
  • 5-HT7 receptor modulators: Amino groups attached to biphenyl scaffold determine functional activity. Kim, Y.; Park, H.; Lee, J.E.; Tae, J.; Kim, H.J.; Min S.-J.; Rhim, H.; Choo, H.* Eur. J. Med. Chem. 2016, 123, 180–190.