추현아, Choo, Hyunah

Principal Researcher

OFFICE

L2215, +82-958-5157

LAB

L2226-7, L2147, +82-958-5167/5120

EDUCATION

Ph.D. Medicinal Chemistry, College of Pharmacy, The University of Georgia at Athens (2003)
M.S. Organic Chemistry, Seoul National University (1996)
B.S. Chemistry, Seoul National University (1993)

RESEARCH CAREER & ACTIVITIES
  • Principal Researcher, Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology (KIST) (2005-Present)
  • Postdoctoral Research Fellow, Department of Medicine, University of California at San Diego (2003-2004)
RESEARCH INTERESTS
  • Discovery of GPCR Modulators (G protein/b-arrestin biased ligands)
  • Discovery of NIR and PET Probes for Diagnosis of Neurodegenerative Diseases
  • Development of Drug Candidates for Depression, Sleep Disorders and AD/PD
HIGHLIGHT
  • A Difluoroboron b-Diketonate Probe Shows “Turn-on” Near-Infrared Fluorescence Specific for Tau Fibrils. Park, K.-s.; Kim, M.K.; Seo, Y.; Ha, T.; Yoo, K.; Hyeon, S.J.; Hwang, Y.J.; Lee, J.; Ryu, H.; Choo, H.*; Chong, Y.* ACS Chem. Neurosci. 2017, 8, 2124–2131.
  • Indole-Substituted Benzothiazoles and Benzoxazoles as Selective and Reversible MAO-B Inhibitors for Treatment of Parkinson’s Disease. Nam, M.-H.; Park, M.; Park, H.; Kim, Y.; Yoon, S.; Sawant, V.S.; Choi, J.W.; Park, J.H.; Park, K.D.; Min, S.-J.; Lee, C.J.; Choo, H.* ACS Chem. Neurosci. 2017, 8, 1519–1529.
  • 5-HT7 receptor modulators: Amino groups attached to biphenyl scaffold determine functional activity. Kim, Y.; Park, H.; Lee, J.E.; Tae, J.; Kim, H.J.; Min S.-J.; Rhim, H.; Choo, H.* Eur. J. Med. Chem. 2016, 123, 180–190.