홍규상, Gyu-Sang Hong

Senior Researcher

OFFICE

L7306, +82-2-958-7036

LAB

L7206, L7406, +82-958-7036

E-mail

gshong@kist.re.kr

HOMEPAGE

https://bsi.kist.re.kr/oh-uhtaek/

EDUCATION

Ph.D. Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Korea (2016)
B.S.  Bio & Nano chemistry Kookmin University, Seoul, Korea (2008)

RESEARCH CAREER & ACTIVITIES

Senior Researcher, Brain Science Institute, Korea Institute of Science and Technology (KIST) (2018-Present)

Postdoctoral Researcher, Senior Researcher, Brain Science Institute, Korea Institute of Science and Technology (KIST) (2016-2018)

Postdoctoral Researcher, Seoul National University (2016)

RESEARCH INTERESTS
  • Sensory perception pathways such as feeling touch, hearing and pain
  • Activation mechanisms of mechanosensitive ion channels
  • The function of ion channels in the developing brain
HIGHLIGHT
  • Hong GS*, Lee SH*, Lee BJ, Jang Y, Jung J, Kim IB, Oh U. ANO1/TMEM16A Regulates Process Maturation in Radial Glial Cells in the Developing Brain. Cell Reports. Under revision.
  • Gyu-Sang Hong, Byeongjun Lee and Uhtaek Oh. Evidence for Mechanosensitive Channel Activity of Tentonin 3/TMEM150C. Neuron, Volume 94, Issue 2, p271–273.e2, 19 April 2017.
  • HONG GS*, Lee B*, Wee J, Chun H, Kim H, Jung J, Cha JY, Riew TR, Kim GH, Kim IB, Oh U. Tentonin 3/TMEM150c Confers Distinct Mechanosensitive Currents in Dorsal-Root Ganglion Neurons with Proprioceptive Function. Neuron, 91, p107-118. June 16, 2016.
  • Cha JY, Wee J, Jung J, Jang Y, Lee B, Hong GS, Chang BC, Choi YL, Shin YK, Min HY, Lee HY, Na TY, Lee MO, Oh U. Anoctamin 1 (TMEM16A) is essential for testosterone-induced prostate hyperplasia. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9722-7. doi: 10.1073/pnas.1423827112. Epub 2015 Jul.
  • Jang Y*, Lee WJ*, Hong GS, Shim WS. Red ginseng extract blocks histamine-dependent itch by inhibition of H1R/TRPV1 pathway in sensory neurons. J Ginseng Res. 2015 Jul;39(3):257-64. doi: 10.1016/j.jgr.2015.01.004. Epub 2015 Jan 22.
  • Jang Y, Kim SW, Oh J, Hong GS, Seo EK, Oh U, Shim WS. Ghrelin receptor is activated by naringin and naringenin, constituents of a prokinetic agent Poncirus fructus. J Ethnopharmacol. 2013 Jul 9;148(2):459-65. doi: 10.1016/j.jep.2013.04.039. Epub 2013 Apr 29.
  • Eijkelkamp N, Linley JE, Torres JM, Bee L, Dickenson AH, Gringhuis M, Minett MS, Hong GS, Lee E, Oh U, Ishikawa Y, Zwartkuis FJ, Cox JJ, Wood JN. A role for Piezo2 in EPAC1-dependent mechanical allodynia. Nat Commun. 2013 4:1682. doi: 10.1038/ncomms2673.