임혜인, Im, Heh-In
Senior Researcher
EDUCATION
Ph.D. Neuroscience, Department of Pharmacology, Seoul National University College of Medicine (2006)
B.S. Veterinary Medicine, Cheju National University (2001)
RESEARCH CAREER & ACTIVITIES
- Senior Researcher, DTC Convergence Center, Brain Science Institute, Korea Institute of Science and Technology (KIST) (2015-present)
- Campus Veterinarian, Research Animal Resources Center (RARC), Korea Institute of Science and Technology (KIST) (2014-present)
- Senior Researcher, Center for Neuroscience, Brain Science Institute, Korea Institute of Science and Technology (KIST) (2012-Present)
- Research Associate, Department of Molecular Therapeutics, The Scripps Research Institute-Florida (TSRI) (2008-2012)
- Postdoctoral Scholar, Department of Psychiatry, University of Chicago (2006-2008)
RESEARCH INTERESTS
- To study for role of various microRNAs in Addiction and its related brain disorders
- To develop de novo therapeutic targets for Alzheimer’s disease
- To develop de novo biomarkers for Addiction and its related brain disorders
HIGHLIGHT
- SYNCRIP controls miR-137 and striatal learning in animal models of methamphetamine abstinence. Kim B, Tag SH, Nam E, HamS, Ahn S, Kim J, Cho DW, Lee S, Yang YS, Lee SE, Kim YS, Cho IJ, Kim KP, Han SC, Im H-I*. Acta Pharm Sin B. 2022, in press
- Dysfunction of striatal MeCP2 is associated with cognitive decline in a mouse model of Alzheimer’s disease. Lee S, Kim TK,Choi JE, Choi Y, You M, Ryu J, Chun YL, Ham S, Hyeon SJ, Ryu H, Kim HS*, Im H-I*. Theranostics. 2022, 12(3)
- Circulating microRNA miR-137 as a stable biomarker for methamphetamine abstinence. Kim B, Tag SH, Kim YS, Cho SN, Im H-I*. Psychopharmacology (Berl). 2022, 239(3)
- Subanesthetic ketamine rapidly alters medial prefrontal miRNAs involved in ubiquitin-mediated proteolysis. Choi Y, Kim B, Ham S, Chung S, Maeng S, Kim HS*, Im H-I*. PLoS One. 2021, 16(8)
- Chronic nicotine impairs sparse motor learning via striatal fast-spiking parvalbumin interneurons. Kim B, Im H-I*. Addict Biol. 2021, 26(3)
- TMEM16A expression in cholinergic neuronsof the medial habenula mediates anxiety-related behaviors. Cho CH, Lee S, KimA, Yarishkin O, Ryoo K, Lee YS, Jung HG, Yang E, Lee DY, Lee B, Kim H, Oh U, Im H-I*, Hwang EM*, Park JY*. EMBO Rep. 2020,21(2)
- Methyl-CpG Binding Protein 2 in Alzheimer Dementia. Kim B, Choi Y, Kim HS, Im H-I*. Int Neurourol J. 2019, 23(Suppl 2)
- Molecular and Cellular Substrates of Neuroinflammation in Alzheimer Disease and Depression. Im H-I*. Int Neurourol J. 2019, 23(Suppl 2)
- The role of the dorsal striatum in choice impulsivity. Kim B, Im H-I*. Ann N Y Acad Sci. 2019, 1451(1)
- Comprehensive MicroRNAome Analysis of the Relationship Between Alzheimer Disease and Cancer in PSEN Double-Knockout Mice. Ham S, Kim TK, Ryu J, Kim YS, Tang YP, Im H-I*. Int Neurourol J. 2018, 22(4)
- Big Data Analysis of Genes Associated With Neuropsychiatric Disorders in an Alzheimer’s Disease Animal Model. Ham S, KimTK, Hong H, Kim YS, Tang YP, Im H-I*. Front Neurosci. 2018, 12
- Regulator of G-protein Signaling 4 (RGS4)Controls Morphine Reward via Glutamate Receptor Activation in the Nucleus Accumbens of the Mouse Brain. Kim J, Lee S, Kang S, Jeon T-I, Kang M-J, LeeT-H, Kim YS, Kim K-S, Im H-I*, Moon C*. Mol Cells. 2018, 41(5)
- Intravenous morphine self-administration alters accumbal microRNA profiles in the mouse brain. Kim J, Im H-I*, Moon C*. Neuroal Regen Res. 2018, 13(1)
- MicroRNA Profiling in Aging Brain of PSEN1/PSEN2 Double Knockout Mice. Ham S, Kim TK, Lee S, Tang YP, Im H-I*. Mol Neurobiol. 2018, 55(6)
- Multiplexed Detection of Epigenetic Markers Using Quantum Dot (QD)-Encoded Hydrogel Microparticles. Yeom SY, Son CH, KimBS, Tag SH, Nam E, Shin H, Kim SH, Gang H, Lee HJ, Choi J*, Im H-I*, Cho IJ*,Choi N*. Anal Chem. 2016, 88(8)
- Integrated miRNA-mRNA analysis in the habenula nuclei of mice intravenously self-administering nicotine. Lee S, WooJ, Kim YS, Im H-I*. Sci Rep. 2015, 5