임혜원, Hyewhon Rhim, Ph.D.

Principal Research Scientist

Director, International Affairs Division

OFFICE

L3518,

+82-2-958-7011

LAB

L7305,

+82-2-958-5905

E-mail

hrhim@kist.re.kr

HOMEPAGE

http://cns.kist.re.kr

EDUCATION

Ph.D. Physiological & Pharmacological Sciences, University of Chicago (1995)

M.S. Chemistry, Seoul National University (1987)

B.S. Chemical Education, Seoul National University (1985)

RESEARCH CAREER & ACTIVITIES
  • Principal Research Scientist, Center for Neuroscience, Brain Science Institute, Korea Institute of Science and Technology (KIST) (2004-Present)
  • Professor, Division of Bio-Medical Science & Technology, KIST School, Korea Institute of Science and Technology (KIST) (2001-Present)
  • President, Korean Society for Brain and Neural Sciences (KSBNS) (2018)
RESEARCH INTERESTS
  • Functional significance of O-GlcNAc modification in neurons
  • Signaling pathways mediated by 5-TH6 receptors
  • Role of autophagy in neurodegeneration
HIGHLIGHT

MG Jo, M Ikram, MH Jo, L Yoo, KC Chung, SY Nah, H Hwang, H Rhim*, MO Kim*. Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway. Molecular Neurobiology, 2018

MA Rahman, H Kim, KH Lee, HM Yun, JH Hong, Y Kim, H Choo, M Park, H Rhim. 5-Hydroxytryptamine 6 Receptor (5-HT6R)-Mediated Morphological Changes via RhoA-Dependent Pathways. Molecules and Cells, 2017

YR Yang, S Song, H Hwang, HJ Jung, SJ Kim, S Yoon, JH Hur, JI Park, C Lee, D Nam, YK Seo, JH Kim, H Rhim*, PG Suh*. Memory and synaptic plasticity are impaired by dysregulated hippocampal O-GlcNAcylation. Scientific Reports, 2017

Y Yang, J Kim, HY Kim, N Ryoo, S Lee, Y Kim, H Rhim*, YK Shin*. Amyloid-β Oligomers May Impair SNARE-Mediated Exocytosis by Direct Binding to Syntaxin 1a. Cell Reports, 2015