Senior Researcher
OFFICE L3326, +82-958-5191
LAB L7425,7426.
E-mail bsjeon@kist.re.kr
HOMEPAGE http://
EDUCATION
Ph.D. Chemistry, The University of Texas at Austin (2017)
M.S. Chemistry, Seoul National University (2004)
B.S. Chemistry, Seoul National University (2002)
RESEARCH CAREER & ACTIVITIES
- Senior Researcher, Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology (KIST) (2019 – Present)
- Postdoctoral Research Fellow, Department of Chemistry, University of California, Berkeley (2017 – 2019)
- Research Scientist, LG Chem. Ltd. (2004 – 2010)
Research Interests
- Organic synthesis for bioactive compounds
- Chemical probes for transition metal signaling
- Mechanistic enzymology and inhibitor design
Highlight
- Byungsun Jeon,Sei-hyun Choi, Namho Kim, Hsin-Hui Wu, Tzu-Ping Ko, Mark W. Ruszczycky, Eta A.Isiorho, Yung-nan Liu, Adrian T. Keatinge-Clay, Ming-Daw Tsai, Hung-wen Liu. J. Am. Chem. Soc. 2021, 143, 20291. Evidence for an Enzyme-CatalyzedRauhut-Currier Reaction during the Biosynthesis of Spinosyn A.
- RinaKwag, Jieon Lee, Doyoung Kim, Haeun Lee, MiyoungYeom, Jiwan Woo, Yakdol Cho, Hak Joong Kim, Jeongjin Kim, Gyochang Keum, ByungsunJeon, Hyunah Choo. J.Med. Chem. 2021, 64, 13766. Discovery of G protein-biased antagonist against 5-HT7 receptors.
- Yang, Z.; Yang, S.; Yu, P.; Li, Y.; Doubleday, C.; Park, J.; Patel, A.; Jeon, B.-s.; Russell, W. K.; Liu, H.-w.; Russell, D. H.; Houk, K. N. “Influence of water and enzyme SpnF on the dynamics and energetics of the ambimodal [6+4]/[4+2] cycloaddition” Proc. Natl. Acad. Sci. USA, 2018, 115, E848-E855.
- Jeon, B.-s.; Ruszczycky, M. W.; Russell, W. K.; Lin, G.-m.; Choi, S.-h.; Kim, N.; Wang, S.-A.; Liu, Y.-n.; Russell, D. H.; Liu, H.-w. “Investigation of the mechanism of the SpnF-catalyzed [4+2]-cycloaddtion reaction in the biosynthesis of spinosyn A” Proc. Natl. Acad. Sci. USA, 2017, 114, 10408-10413.
- Jeon, B.-s.; Wang, S.-A.; Ruszczycky, M. W.; Liu, H.-w. “Natural [4+2]-Cyclases” Chem. Rev. 2017, 117, 5367-5388.