박한범, Park, Hahnbeom

Senior Researcher

OFFICE

L7431B, +82-958-5136

LAB

L7434

EDUCATION

Ph.D. Physical Chemistry, Department of Chemistry, Seoul National University (2012)

B.S. Chemistry,  Department of Chemistry, Seoul National University (2007)

RESEARCH CAREER & ACTIVITIES
  • Senior Researcher, Brain Science Institute,  Korea Institute of Science and Technology (KIST) (2021-Present)
  • Acting Instructor,  Department of Biochemistry, Univ. of Washington (2019~2021)
  • Postdoctoral research fellow,  Department of Biochemistry, Univ. of Washington (2012~2018)
RESEARCH INTERESTS
  • Drug discovery using Artificial Intelligence and Deep learning
  • Biomedicine Design
  • Biomolecular modeling software development
HIGHLIGHT

  • N. Hiranuma1, H. Park1 (co-first), M. Baek, I. Anishchanka, J. Dauparas, D. Baker. Improved protein structure refinement guided by deep learning based accuracy estimation, Nature Comm. 12, 1340, 2021.

  • H. Park, G. Zhou, M. Baek, D. Baker, F. DiMaio. Force Field Optimization Guided by Small Molecule Crystal Lattice Data Enables Consistent Sub-Angstrom Protein–Ligand Docking. J Chem Theory Comput., 17, 2000-2010, 2021. (Rosetta GALigandDock and GenFF paper)

  • H. Park, S. Ovchinnikov, D. E. Kim, F. DiMaio, D. Baker, Protein homology model refinement by large scale energy optimization, Proc Natl Acad Sci USA 115, 3054-3059, 2018. 

  • S. Ovchinnikov, H. Park, N. Varghese, P. Huang, G. A. Pavlopoulos, D. E. Kim, H. Kamisetty, N. C. Kyrpides, and D. Baker, Protein structure determination using metagenome sequence data, Science 355, 294-298, 2017. 

  • H. Park, P. Bradley, P. Greisen Jr., Y. Liu, V. K. Mulligan, D. E. Kim, D. Baker, and F. DiMaio. Simultaneous optimization of biomolecular energy function on features from small molecules and macromolecules, J Chem Theory Comput. 12, 6201-6212, 2016. (Rosetta standard energy function “ref2015” paper)