박종현, Jong-Hyun Park Ph.D.

• Researcher, Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST) (2018-Present)
• Postdoctoral Researcher, Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST) (2016-2018)
• Postdoctoral Researcher, Center for Neuro-medicine, Brain Science Institute, Korea Institute of Science and Technology (KIST) (2014-2016)

• Evaluation and validation of efficacy of therapeutic agents for brain diseases

– Cell-based drug efficacy assessment of target protein

– Animal model (Dementia, Parkinson’s disease, multiple sclerosis) based drug efficacy assessment

– Establishment and optimization of a new target drug evaluation system

• Synthesis and evaluation of biaryl derivatives for structural characterization of selective monoamine oxidase B inhibitors toward Parkinson’s disease therapy. Yeon SK*, Choi JW*, Park J-H*, Lee YR*, Kim HJ, Shin SJ, Jang BK, Kim S, Bahn YS, Han G, Lee YS, Pae AN and Park KD. Bioorganic & Medicinal Chemistry, 2018, 26(1):232-244
• Membrane-bound Dickkopf-1 in Foxp3+ regulatory T cells suppresses T-cell-mediated autoimmune colitis. Chae WJ, Park J-H, Henegariu O, Yilmaz S, Hao L and Bothwell AL. Immunology, 2017, 152(2):265-275
• Screening, Synthesis, and In Vitro Evaluation of Vinyl Sulfones as Inhibitors of Complement-Dependent Cytotoxicity in Neuromyelitis Optica. Ju EJ*, Yeon SK*, Park J-H*, Cheon SY, Choi JW, Ha T, Jang BK, Kim S, Kang YG, Hwang H, Cho SJ, Cheong E, Bahn YS, Pae AN, Kim SM and Park KD. ChemMed Chem, 2016, 11(4):377-381
• The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation. Chae WJ, Ehrlich AK, Chan PY, Teixeira AM, Henegariu O, Hao L, Shin JH, Park J-H, Tang WH, Kim ST, Maher SE, Goldsmith-Pestana K, Shan P, Hwa J, Lee PJ, Krause DS, Rothlin CV, McMahon-Pratt D and Bothwell AL. Immunity, 2016, 44(2):246-258
• Antioxidant and Anti-Inflammatory Activities of a Natural Compound, Shizukahenriol, through Nrf2 Activation. Park J-H, Choi JW, Ju EJ, Pae AN and Park KD. Molecules 2015 20(9):15989-16003