배애님, Pae, Ae Nim
Principal Researcher
EDUCATION
Ph.D. Medicinal Chemistry, Department of Chemistry, Korea University (1997)
M.S. Department of Chemistry, KAIST (1988)
B.S. Chemistry, Duksung Women’s University (1985)
RESEARCH CAREER & ACTIVITIES
- Head, Convergence Research Center for Dementia (DTC), KIST, Korea Institute of Science and Technology (KIST) (2015-Present)
- Head, Center for Neuro-Medicine, KIST, Korea Institute of Science and Technology (KIST) (2009-2015)
- Principal Researcher, Korea Institute of Science and Technology (KIST) (2005-Present)
- Visiting Scientist, Department of Pharmacy, University of Illinois at Chicago (2014)
- Postdoctoral Research Fellow, Department of Chemistry, University of Illinois at Urbana-Champaign (1999-2000)
- Senior Research Scientist, Korea Institute of Science and Technology (KIST) (1997-2004)
- Researcher, Korea Institute of Science and Technology (KIST) (1988-1997)
RESEARCH INTERESTS
- Discovery of therapeutic agents for Brain Disease such as Alzheimer’s Disease, multiple sclerosis and neuropathic Pain.
- Chemoinformatics–based drug design and novel scaffold identification by virtual screening
HIGHLIGHT
- Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer’s disease, Kim, T.H;Yang, H.Y.;Park, B.K.;Jung, S.Y.;Park,J.H.;Park, K.D.;Min, S.J.;Tae, J.S.;Yang, H.J.;Cho, S.M.;Cho, S.J.;Song, H.D.;Mook-Jung, I.;Lee, J.;PAe, A.N. Eur. J. Med. Chem, 2017, 125, 1172-1192
- Pharmacophore-based virtual screening, biological evaluation and binding mode analysis of a novel protease-activated receptor 2 antagonist, Cho, N.C.;Seo, S.H.;Kim, D.H.;Shin, J.S.;Ju, J.Seo, S.H.;Lee,J.Y.;Lee, K.T.;Kim, Y.K.;No, K.T;Pae, A.N J. Com. Aid. Mol. Des, 2016, 30(8), 625-637
- Synthesis and Biological Evaluation of Aryloxazole Derivatives as Antimitotic and Vascular-Disrupting Agents for Cancer Therapy, Choi, M.J.; No, E.S.;Thorat, D.A.; Jang, J.W.; Yang, H.K, Lee, J.; Choo, H. Kim, S.J.; Lee, C.S.; Ko, S. Y.; Lee, J.; Nam, G.; Pae, A. N. J. Med. Chem, 2013, 56(22), 9008
- Receptor-Ligand Interaction-Based Virtual Screening for Novel Eg5/Kinesin Spindle Protein Inhibitors, Nagarajan, S.; Skoufias, D.A.; Kozielski, F.;Pae, A.N J. Med. Chem. 2012, 55(6), 2561